Atrial Septal Defect (ASD) : This is a congenital heart defect in which blood flows between the atria (upper chambers) of the heart. A wall called the Interatrial Septum separates the Atria. If this septum is defective or absent, then oxygen-rich blood can flow directly from the left side of the heart to mix with the oxygen-poor blood in the right side of the heart, or vice versa. This causes lower-than-normal oxygen levels in the arterial blood that supplies the brain, organs, and tissues.
Ventricular Septal Defect (VSD) :This is a defect in the ventricular septum, the wall dividing the left and right ventricles (lower chambers) of the heart. The extent of the opening may vary from pin size to complete absence of the ventricular septum, creating one common ventricle. The ventricular septum consists of an inferior muscular and superior membranous portion and is extensively innervated with conducting cardiomyocytes (cardiac muscle cells).
Patent Ductus Arteriosus (PDA) :This is a condition wherein the ductus arteriosus (fetal blood vessel) fails to close after birth. This vessel does not close and remains "patent" (open), resulting in irregular transmission of blood between the aorta and the pulmonary artery. PDA is common in newborns with persistent respiratory problems such as hypoxia and has a high occurrence in premature newborns due to underdevelopment of the heart and lungs.